Giorgio Lenaz Selected Research

Neuropathy ataxia and retinitis pigmentosa

8/2009	Human NARP mitochondrial mutation metabolism corrected with alpha-ketoglutarate/aspartate: a potential new therapy.
7/2008	The study of the pathogenic mechanism of mitochondrial diseases provides information on basic bioenergetics.
5/2006	Inefficient coupling between proton transport and ATP synthesis may be the pathogenic mechanism for NARP and Leigh syndrome resulting from the T8993G mutation in mtDNA.
2/2002	Biochemical-clinical correlation in patients with different loads of the mitochondrial DNA T8993G mutation.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Giorgio Lenaz Research Topics

Disease

4	Leber Hereditary Optic Atrophy (Leber's Hereditary Optic Neuropathy) 02/2012 - 07/2004
4	Neuropathy ataxia and retinitis pigmentosa 08/2009 - 02/2002
4	Mitochondrial Diseases (Mitochondrial Disease) 07/2006 - 07/2004
2	Hypoxia (Hypoxemia) 02/2013 - 06/2010
2	Parkinson Disease (Parkinson's Disease) 12/2008 - 09/2006
2	Neurodegenerative Diseases (Neurodegenerative Disease) 12/2008 - 09/2006
2	Osteosarcoma (Osteogenic Sarcoma) 06/2006 - 01/2004
2	Leigh Disease (Leigh's Disease) 05/2006 - 02/2002
1	Neoplasms (Cancer) 02/2013
1	Maternally Inherited Leigh Syndrome 08/2009
1	Alzheimer Disease (Alzheimer's Disease) 10/2007
1	Virus Diseases (Viral Diseases) 08/2006
1	Infections 08/2006
1	Carcinoma (Carcinomatosis) 06/2006
1	Nervous System Diseases (Neurological Disorders) 05/2006
1	MELAS Syndrome (Syndrome, MELAS) 07/2004
1	Fatty Liver 07/2004
1	Ischemia 03/2004
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 02/2002

Drug/Important Bio-Agent (IBA)

11	Mitochondrial DNA (mtDNA)IBA 02/2013 - 02/2002
4	Adenosine Triphosphate (ATP)IBA 08/2009 - 02/2002
3	Reactive Oxygen Species (Oxygen Radicals)IBA 06/2010 - 09/2006
2	Succinic Acid (Succinate)IBA 02/2013 - 07/2004
2	Adenosine Triphosphatases (ATPase)IBA 06/2010 - 07/2008
2	EnzymesIBA 12/2008 - 09/2006
2	Protons (Proton)IBA 09/2006 - 05/2006
2	Electron Transport Complex IV (Cytochrome c Oxidase)IBA 07/2004 - 01/2004
1	NAD (NADH)IBA 02/2013
1	MitogensIBA 02/2013
1	MutagensIBA 02/2013
1	Amino Acids FDA Link 02/2012
1	idebenoneIBA 02/2012
1	Nonsense Codon (Nonsense Mutation)IBA 02/2012
1	Proteins (Proteins, Gene)FDA Link 06/2010
1	Hypoxia-Inducible Factor 1IBA 06/2010
1	Oxygen (Dioxygen)IBA 06/2010
1	Adenosine (Adenocard)FDA LinkGeneric 08/2009
1	Proton-Translocating ATPases (ATPase, H+)IBA 07/2008
1	PolyaminesIBA 10/2007
1	quinone (benzoquinone)IBA 10/2007
1	LigandsIBA 10/2007
1	LipidsIBA 08/2006
1	Peptides (Polypeptides)IBA 08/2006
1	DNA (Deoxyribonucleic Acid)IBA 06/2006
1	malic acid (malate)IBA 07/2004
1	Glutamic Acid (Glutamate)FDA Link 07/2004
1	Antimycin AIBA 03/2004
1	NucleotidesIBA 01/2004
1	Oxidoreductases (Dehydrogenase)IBA 02/2002

Therapy/Procedure

1	Therapeutics 10/2007
1	Transplantation 07/2004